Engineering amino acid-derived malonyl-CoA pathways to boost polyketide production in Yarrowia lipolytica.

Malonyl-CoA is a central precursor involved in the synthesis of various bio-based chemicals, including polyketides, fatty acids, and flavonoids. However, the production of these chemicals is often limited by the availability of malonyl-CoA. Based on…

Preview only. Read the full abstract at the source