Journal of molecular and cellular cardiologyvon Willebrand FactorAnimalsThrombosisHumansHomocysteine
Homocysteine activates endothelial TP receptor to promote von Willebrand factor secretion and thrombosis.
Jiachen Zhang, Xinyu Jia, Ping Zhu, Mengzheng Zhao, Haodong Du, Xinyi Yu, Jing Huang, Yegong Xie, Yequn Chen, Yi Zhu, Qiankun Bao, Jinlong He, Liu Yao
Published: 202610.1016/j.yjmcc.2025.10.013
Abstract
Hyperhomocysteinemia (HHcy), characterized by elevated plasma homocysteine (Hcy) levels, is a recognized risk factor for thrombosis and an independent contributor to acute coronary syndrome, although its underlying mechanisms are not fully understood…
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