Journal of molecular and cellular cardiologyAnimalsReceptorsAryl HydrocarbonMyocardial InfarctionFibrosis
Beneficial effects of aryl hydrocarbon receptor activation on post-infarction myocardial metabolism, inflammation and fibrosis: implications from multi-omics.
Yong Chu, Jiang Zhu, Shuaijie Chen, Xiaoyan Lin, Zhongxing Zhou, Ruming Shen, Hongzhuang Wang, Longqing Chen, Jinxiu Lin, Hailin Zhang, Dajun Chai
Published: 202510.1016/j.yjmcc.2025.10.006
Abstract
BACKGROUND: Post-infarction metabolism changes, inflammatory responses, and fibrosis are crucial contributors to adverse cardiac remodeling. 2-(1'H-indole-3'‑carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE), the aryl hydrocarbon receptor (AHR)…
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