Gynecologic oncologyHumansMast CellsFemaleNeoadjuvant TherapyCystadenocarcinoma
Neoadjuvant chemotherapy modulates mast cell phenotypes and immune infiltration in high-grade serous carcinoma.
Yuanchun Fan, Qiuman Wang, Huiyan Deng, Yueping Liu, Hui Zhang
Published: 202510.1016/j.ygyno.2025.10.014
Abstract
OBJECTIVE: The influence of neoadjuvant chemotherapy (NACT) on the immune landscape of high-grade serous carcinoma (HGSC) remains inadequately understood. This study aims to investigate the differential patterns of immune infiltration in HGSC tissues…
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