Frontiers in neuroendocrinologyHumansMitochondriaNeurodegenerative DiseasesAnimalsGlucagon-Like Peptides
Semaglutide and the pathogenesis of progressive neurodegenerative disease: the central role of mitochondria.
George B Stefano, Pascal Büttiker, Simon Weissenberger, Jiri Raboch, Martin Anders
Published: 202510.1016/j.yfrne.2025.101217
Abstract
While mitochondria provide critical energy resources, mitochondrial dysfunction can lead to both metabolic and neurodegenerative disorders. Primary mitochondrial disorders (e.g., Leigh syndrome) are uniformly associated with profound neurodegeneratio…
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