Experimental and molecular pathologyHumansGlycocalyxBiomarkersSyndecan-1Critical Illness
Glycocalyx shedding as a clinical biomarker in critical illness.
Ayako Inoda, Keiko Suzuki, Hiroyuki Tomita, Hideshi Okada
Published: 202510.1016/j.yexmp.2025.104997
Abstract
The endothelial glycocalyx, a carbohydrate-rich layer lining the vascular endothelium, plays a critical role in maintaining vascular homeostasis by regulating permeability, leukocyte adhesion, and inflammatory signaling. Its degradation has been impl…
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