Experimental cell researchHumansTumor MicroenvironmentColorectal NeoplasmsCancer-Associated FibroblastsTumor-Associated Macrophages
Metabolic adaptation in colorectal cancer microenvironment: Focus on cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs).
Chou-Yi Hsu, Amr Ali Mohamed Abdelgawwad El-Sehrawy, Mirza R Baig, Zahraa Khudhair, Saidmurodkhon Murtazaev, Pareshkumar N Patel, Subbulakshmi Ganesan, Vimal Arora, Sandeep Kumar Shukla, Priya Priyadarshini Nayak
Published: 202610.1016/j.yexcr.2025.114867
Abstract
Metabolic reprogramming within the tumor microenvironment (TME) is a critical driver of colorectal cancer (CRC) progression, influencing tumor growth, immune evasion, and metastatic dissemination. Cancer-associated fibroblasts (CAFs) undergo adaptive…
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