Experimental cell researchHumansEverolimusCaco-2 CellsApoptosisCircadian Rhythm
Effects of everolimus on circadian gene expression and cell fate in synchronized Caco-2 cells.
Dilek Ozturk Civelek, Beyza Goncu, Sadullah Goncu, Alper Okyar
Published: 202510.1016/j.yexcr.2025.114810
Abstract
OBJECTIVES: Circadian rhythms regulate key biological processes, including cell proliferation and metabolism, and their disruption is implicated in colorectal cancer (CRC). mTOR signaling interacts bidirectionally with the circadian clock, yet how mT…
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