Experimental cell researchFerroptosisHumansGliomaMembrane ProteinsCell Line
FERMT1 suppresses the ferroptosis of glioma cells by interacting with MBOAT2.
Zhigang Pan, Chuhan Ke, Bojun Zhang, Qingxin Lin, Hanlin Zheng, Shuni Zheng, Jinzhong Huang, Weipeng Hu
Published: 202510.1016/j.yexcr.2025.114794
Abstract
Gliomas, particularly high-grade glioblastomas, are highly aggressive malignancies with limited treatment options and poor prognosis. Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a promising…
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