Developmental biologyAnimalsZebrafishRegenerationMyocytesCardiac
Epicardial Tcf21 facilitates cardiomyocyte dedifferentiation and heart regeneration in zebrafish.
Miglė Kalvaitytė-Repečkė, Sofija Gabrilavičiūtė, Kotryna Kvederavičiūtė, Leonard Burg, Edita Bakūnaitė, Kenneth D Poss, Darius Balciunas
Published: 202610.1016/j.ydbio.2025.12.004
Abstract
Unlike mammals, zebrafish (Danio rerio) are able to regenerate their hearts after injury, making them an excellent model organism for studying the molecular mechanisms underlying heart regeneration. Epicardium, the outermost layer of the heart, is an…
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