Direct activation of folate receptor 4 by thyroid hormone suggests its role in the development of adult intestinal epithelium during Xenopus laevis metamorphosis.

Amphibian metamorphosis is tightly regulated by thyroid hormone (TH). During this process, most larval epithelial cells in the Xenopus laevis intestine undergo apoptosis, whereas a small population dedifferentiates into adult epithelial stem cells. T…

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