Developmental biologyAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsGerm CellsEmbryo
Poly(U) polymerase activity promotes establishment of primordial germ cells and limits somatic PGL granules in the Caenorhabditis elegans embryo.
Leanne H Kelley, Ashley S Houlihan, Kevin E Yongblah, Abrar A Aljiboury, Savannah L Davis, Eleanor M Maine
Published: 202610.1016/j.ydbio.2025.10.013
Abstract
Terminal uridylyl transferases/poly(U) polymerases (PUPs) promote animal development. Under conditions of temperature stress, Caenorhabditis elegans PUP-1 and the partially redundant PUP-2 ensure development of the larva/adult germline and embryonic…
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