Journal of pharmaceutical sciencesExcipientsMultivariate AnalysisPrincipal Component AnalysisAdministrationOral
Understanding the impact of excipient variability on oral solid dosage form performance: A possible role for multivariate data analysis, in the form of principal component analysis.
Pauline H M Janssen, Bastiaan H J Dickhoff, Ana Ferreira, John Gamble, Rachael Shinebaum, Mike Tobyn
Published: 202510.1016/j.xphs.2025.104021
Abstract
The development of a robust oral solid dosage form requires knowledge of all the sources of variation that could impact the dosage form's performance and stability. One of those sources of variability is in the excipients that can make up the bulk of…
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