Vascular pharmacology
Endothelial-to-mesenchymal transition primes vascular endothelial cells toward an osteochondrogenic fate.
Franceska Kishta, Ignacio Fernando Hall, Guanliang Li, Tanushree Tripathi, Matthieu Vermeren, Justyna Cholewa-Waclaw, Fiona Rossi, Bruno M Péault, Julie Rodor, Abdelaziz Beqqali, Judith C Sluimer, Mihaela Crisan, Andrew H Baker
Published: 202510.1016/j.vph.2025.107579
Abstract
Endothelial-to-mesenchymal transition (EndMT), in which endothelial cells (ECs) lose their endothelial identity and acquire mesenchymal-like features, contributes to vascular dysfunction and remodeling in atherosclerosis. However, the fate and functi…
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