Veterinary microbiologyAnimalsChickensInfluenza A VirusH9N2 SubtypeCoinfection
Synergistic virulence of H9N2 AIV and APEC co-infection in laying hens involves a critical role for macrophage-mediated hyper-inflammation via the MAPK/NF-κB axis.
Jinjie Han, Wenchi Chang, Zhaoyue Jing, Dong Xiao, Tiantian Ji, Junyang Fang, Mengzhao Song, Wei Li, Jingyu Wang, Wen Deng
Published: 202610.1016/j.vetmic.2025.110846
Abstract
H9N2 avian influenza virus (AIV) is a low-pathogenic subtype virus that is widely prevalent in poultries worldwide. Although H9N2 infection alone typically causes mild or asymptomatic disease in chickens, it facilitates secondary bacterial infections…
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