Veterinary immunology and immunopathologyAnimalsAdjuvantsImmunologicImmunityInnate
Intradermal administration of a novel adjuvant cyclopolyphosphazene (CPZ-75B) in pigs induces innate immune responses comparable to poly[di(sodiumcarboxylatoethylphenoxy)phosphazene] (PCEP).
Dylan J Chand, Rani Kanthan, Kezia R Fourie, Leonie Bettin, Pooja Choudhary, Donaldson Magloire, Haoming Liu, Alison Jeffery, Barbara Ribeiro de Souza Cortez, Siew Hon Ng, Royford B Magiri, Heather L Wilson, George K Mutwiri
Published: 202610.1016/j.vetimm.2025.111061
Abstract
In the present study, we evaluated innate immune responses induced by a novel cyclopolyphosphazene called CPZ-75B in piglets in the absence of antigen. Furthermore, we compared responses induced by this novel CPZ-75B adjuvant to PCEP, a known polypho…
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