Veterinary immunology and immunopathologyAnimalsQuinolizinesMatrinesDogsAlkaloids
Matrine as a potent inhibitor of canine mammary tumors: Insights from network pharmacology, molecular docking, molecular dynamics and in vitro analysis.
Fida Noor, Wenwen Ding, Na Sun, Panpan Sun, Huizhen Yang, Hua Zhang, Kuohai Fan, Wei Yin, Zhenbiao Zhang, Yaogui Sun, Jianzhong Wang, Jia Zhong, Hongquan Li
Published: 202510.1016/j.vetimm.2025.111020
Abstract
Canine mammary tumor (CMT) is the most prevailing neoplasms in female dogs. Matrine demonstrates anti-tumor effects in various organs, its mechanism in CMT treatment remains unclear. This study involved in network pharmacology, molecular docking, dyn…
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