VaccineHumansCiprofloxacinDoxycyclineAdultMale
Effect of Co-administration of the anthrax vaccine adsorbed, adjuvanted with ciprofloxacin or doxycycline on antibiotic pharmacokinetics and the vaccine immunogenicity: A phase 2 drug-vaccine interaction study.
Bojan Drobic, Gideon Akintunde, Julia Kim, Mila Mirceta, Marinda Beach, Vanja Komlenovic
Published: 202610.1016/j.vaccine.2025.128135
Abstract
BACKGROUND: CYFENDUS® vaccine (Anthrax Vaccine Adsorbed, Adjuvanted) with the recommended antibacterial drugs is licensed for post-exposure prophylaxis (PEP) following suspected or confirmed Bacillus anthracis exposure. This pre-licensure study exami…
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