VaccineAnimalsPneumococcal VaccinesMiceBacterial ProteinsImmunoglobulin A
NKT cell-dependent PspA-specific IgA production caused by mucosal administration of a novel nanoparticle pneumococcal vaccine.
Ayako Nakahira, Hiroki Iwaoka, Ko Sato, Shigenari Ishizuka, Ryuhei Shiroma, Tomomitsu Miyasaka, Emi Kanno, Hiromasa Tanno, Yuki Sato, Yukihiro Akeda, Kazunori Oishi, Tetsuji Aoyagi, Keiko Ishii, Kazuyoshi Kawakami
Published: 202510.1016/j.vaccine.2025.127911
Abstract
Pneumonia is one of the leading causes of death worldwide, with Streptococcus pneumoniae being a major causative agent of community-acquired pneumonia. In immunocompromised infants and the elderly, this pathogen can invade the bloodstream and cerebro…
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