VaccineImmunoglobulin ASARS-CoV-2HumansMucous MembraneMale
Comparing methods collecting mucosal secretions and detecting SARS-CoV-2 spike IgA in three laboratories across three countries.
Oscar Bladh, Katherina Aguilera, Salma Sheikh-Mohamed, Jessica Nardulli, Disha Bhavsar, Dylan Fitzgerald, Gagandeep Singh, Lesley A Ward, Giulio Kleiner, Gary Y C Chao, Nina Greilert Norin, Tamás Pongrácz, Charles Gleason, Matilda Berkell, Mikael Åberg
Published: 202510.1016/j.vaccine.2025.127792
Abstract
BACKGROUND: Mucosal IgA is key in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Several mucosal vaccines are in development, and consistent methodologies assessing mucosal IgA are crucial for evaluation across cl…
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