Should Gleason 6 Still Be Considered Cancer? A Narrative Review of its Biology and Clinical Course, with Implications for Guideline Recommendations and Practice Implementation.

Gleason 6 prostate cancer, also classified as grade group 1 (GG1), demonstrates exceptionally indolent behavior with minimal risk of metastasis or mortality. Despite this, its designation as cancer drives overdiagnosis, overtreatment, and patient anx…

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