Tuberculosis (Edinburgh, Scotland)HumansTuberculosisMeningealCell-Free Nucleic AcidsMycobacterium tuberculosis
Diagnosing tuberculous meningitis from cell-free DNA by multi-targeted real-time PCR: An experience from 170 cases.
Kusum Sharma, Megha Sharma, Ritu Shree, Neeraj Singla, Himanshu Joshi, Ashish Kumar Kakkar, Apinderpreet Singh, Aman Sharma, Navneet Sharma, Manish Modi
Published: 202510.1016/j.tube.2025.102705
Abstract
SETTING: and objective: To evaluate the diagnostic utility of Cell-free DNA (Cf-DNA)-based multi-targeted real-time PCR (Mrt-PCR) for diagnosing tuberculous meningitis, the most severe form of extrapulmonary tuberculosis. DESIGN: A total of 170 cereb…
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