Tuberculosis (Edinburgh, Scotland)Mycobacterium tuberculosisAnimalsToxin-Antitoxin SystemsGuinea PigsBacterial Proteins
Understanding the role of PezAT and MbcTA toxin-antitoxin systems in the pathophysiology of Mycobacterium tuberculosis.
Manisha Singh, Deepika Chaudhary, Arun Sharma, Sonu Kumar Gupta, Imran Ahmad, Yashwant Kumar, Ramandeep Singh
Published: 202510.1016/j.tube.2025.102703
Abstract
Toxin antitoxin (TA) systems are bicistronic genetic elements encoding for a stable toxin and its cognate labile antitoxin. The genome of Mycobacterium tuberculosis (M. tuberculosis) encodes a large repertoire of TA systems and these are highly conse…
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