Translational research : the journal of laboratory and clinical medicine
B-cell activation underpins Rituximab response in focal segmental glomerulosclerosis.
Liangjian Lu, Chang Yien Chan, Mya Than, Sharon Teo, Perry Yw Lau, Kong-Peng Lam, Kar Hui Ng, Hui Kim Yap
Published: 202610.1016/j.trsl.2026.01.002
Abstract
The pathogenesis of primary focal segmental glomerulosclerosis (FSGS) is incompletely understood, and outcomes remain poor. Some patients respond to Rituximab, especially patients who have hyporesponsive T-cells, but the underlying mechanism is unkno…
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