Transplant immunologyHumansGraft RejectionMacrophagesOrgan TransplantationAnimals
Macrophage polarization in organ transplantation rejection and targeted therapeutic strategies.
Changqing Qu, Yi Chen, Xiaoyu Xu, Xianduo Li, Dongdong Chen, Wenzhi Du, Minrui Zhang, Zhe Yang, Jianning Wang
Published: 202510.1016/j.trim.2025.102316
Abstract
Organ transplantation improves survival and quality of life in end-stage organ failure, but rejection remains a key barrier to long-term graft success. While current immunosuppression primarily targets adaptive immunity, its limitations and side effe…
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