Toxicology letters
An integrated in vitro and in silico testing strategy applied to PFAS inhibition of antibody production to define a tolerable daily intake.
Martina Iulini, Aafke W F Janssen, Karsten Beekmann, Giulia Russo, Francesco Pappalardo, Styliani Fragki, Alicia Paini, Emanuela Corsini
Published: 202610.1016/j.toxlet.2025.111817
Abstract
Per- and polyfluoroalkyl substances (PFAS) are widely used chemicals known for their persistence, bioaccumulation, and adverse health effects, particularly on the immune system. Epidemiological studies link PFAS exposure to immunosuppression, with in…
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