Toxicology lettersAnimalsOrganoidsSpecies SpecificityIntestineSmall
Evaluation of interspecies differences in DS-2087b-induced gastrointestinal toxicity using mouse and monkey intestinal organoids.
Yuji Shirai, Takuma Iguchi, Kazunori Fujimoto, Masako Imaoka, Yuko Hasegawa, Katsuyoshi Chiba
Published: 202610.1016/j.toxlet.2025.111805
Abstract
Gastrointestinal (GI) toxicity is a common adverse event induced by anti-cancer drugs; however, the information of the correlations in vitro to in vivo regarding GI toxicity is limited. The objective of this study was elucidating the usefulness of an…
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