Toxicology lettersAnimalsHumansMiceRANK LigandMicroplastics
RANKL/OPG axis as a therapeutic target for microplastic-induced bone loss: Mechanistic insights from transcriptomic and functional validation.
Weilin Zhang, Kuize Liu, Boyuan Zhou, Dao Feng, Zhencong Li, Zhiwen Dai, Shengbang Huang, Jinguo Liang, Siyuan Chen, Zhongwei Wang, Weixiong Guo, Chao Mao, Yen Wei, Jinsong Wei
Published: 202610.1016/j.toxlet.2025.111789
Abstract
Although plastic products have offered substantial benefits to modern society and daily life, their degradation into microplastics (MPs) has raised significant concerns owing to their adverse effects on ecosystems and human health. This study investi…
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