Beyond structural divergence: Multiscale computational immunogenicity modelling of botulinum neurotoxin E and cross-reactivity in botulinum neurotoxin A primed hosts.

Botulinum neurotoxin type E (BoNT/E) is clinically attractive for its rapid onset and short duration of effect but carries uncertain immunogenic risks. Using sequence analysis, structural modelling, and immunoinformatics and multiscale computational…

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