ToxicologyAnimalsFerroptosisSwineAflatoxin B1Signal Transduction
The combined exposure to AFB1 and DON induces the ferroptosis of porcine intestinal epithelial cells via down-regulating PI3K-AKT signal pathway.
Wenshuo Zhao, Qirui Yang, Yuqi Song, Yuhang Sun
Published: 202610.1016/j.tox.2025.154343
Abstract
Aflatoxin B1 (AFB1) and deoxynivalenol (DON) are two highly hazardous mycotoxins often coexisting in feed, threating animal intestinal health. Ferroptosis, a regulated cell death linked to iron metabolism disorders, lipid peroxidation, and amino acid…
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