Trends in pharmacological sciencesHumansAlzheimer DiseaseAnimalsSirtuins
Sirtuins in Alzheimer's disease: mechanistic insights and therapeutic opportunities.
Ning Bai, Shuhui Liu, Jiayi Wei, Biyu Zheng, Weiye Wang, Xiaoman Li, Jiaming Yang, Xiaoyu Song, Liang Wang, Fei Yi, Liu Cao
Published: 202610.1016/j.tips.2025.10.016
Abstract
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder characterized by progressive cognitive decline and complex neuropathology. Its main features include amyloid-β (Aβ) plaques, tau neurofibrillary tangles (NFTs), and neuroinflammat…
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