Trends in pharmacological sciencesDopamine Plasma Membrane Transport ProteinsHumansAnimalsDrug DiscoverySubstance-Related Disorders
Discovering next-generation dopamine transporter drugs with lower abuse potential.
Ding Luo, Zerong Liu, Weiwei Xue
Published: 202510.1016/j.tips.2025.10.002
Abstract
Many traditional psychostimulants used to treat neuropsychiatric disorders by targeting the dopamine transporter (DAT) exhibit a high potential of abuse. This necessitates the development of next-generation drugs with improved safety. Discovering aty…
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