Tissue & cell
Integrative multi-omics profiling implicates purine metabolism and the PI3K-Akt pathway in radiation-induced lung injury.
Jun Qiu, Xinpan Li, Yi Fang, Qiaoyuan Wu, Shixiong Liang
Published: 202610.1016/j.tice.2026.103330
Abstract
BACKGROUND: Thoracic radiotherapy commonly causes radiation-induced lung injury (RILI); however, its mechanisms remain poorly defined, and no FDA-approved therapies are available. METHODS: To identify key pathways and regulators, we analyzed metaboli…
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