Tissue & cell
HAX1 overexpression induces osteogenic differentiation of periodontal ligament stem cells via the MEK/ERK signaling cascade.
Peiqi Hao, Xin-Yu Zhang, Mengting Wang, Fan Bao, Hui Guo
Published: 202610.1016/j.tice.2026.103311
Abstract
BACKGROUND: Periodontitis is characterized by periodontal tissue destruction and subsequent tooth loss, significantly impacting quality of life. The potential of HAX1, a gene implicated in periodontitis pathogenesis, to modulate the differentiation o…
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