Tissue & cell
Protective effects of polydatin on cyclophosphamide-induced ovarian and uterine damage in rats via modulation of hormonal, oxidative, inflammatory, and histopathological alterations.
Ramazan Bülbül, Sefa Küçükler, Selim Çomaklı, Özge Kandemir, Elif Dalkılınç, Sevda Sağ Bayav, Cuneyt Caglayan, Fatih Mehmet Kandemir
Published: 202610.1016/j.tice.2026.103309
Abstract
Cyclophosphamide (Cyclo) is a chemotherapeutic agent whose clinical use is limited by its toxic effects on ovarian and uterine tissues. Polydatin (Poly), a resveratrol derivative with antioxidant and anti-inflammatory properties, was evaluated for it…
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