Tissue & cell
Melatonin attenuates chronic obstructive pulmonary disease by suppressing NLRP3-mediated pyroptosis in alveolar macrophages.
Xiaofeng Li, Zhe Wang, Meng Shi, Tingting Zhang, Sha Huang, Xiaoju Liu
Published: 202510.1016/j.tice.2025.103305
Abstract
Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation and emphysema and is induced primarily by cigarette smoke (CS) exposure. Emerging evidence suggests that alveolar macrophage (AM) pyroptosis contributes to COPD path…
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