Tissue & cell
Empagliflozin as a potential therapy for PCOS: Restoring hormonal balance and ovarian function in a letrozole-induced rat model.
Heba A Habib, Mahmoud El-Daly, Yahya I Asiri, Saud Alqahtani, Eman M Awad, Sara Mn Abdel Hafez, Al-Shaimaa F Ahmed, Aliaa F Anter
Published: 202510.1016/j.tice.2025.103298
Abstract
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder that often leads to infertility. The characteristic hyperandrogenemia and elevated luteinizing hormone /follicle stimulating hormone ratio, resulting in ovulation failur…
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