Tissue & cellAnimalsForkhead Box Protein O3RatsSprague-DawleySirtuin 1
Targeted renal cyto-protection by medicarpin against acyclovir-induced nephrotoxicity via regulating SIRT1/FOXO3a and endothelin axis: An experimental and computational analysis.
Hesham M Hassan, Abdulaziz Saleh Alkhoshaiban, Aqsa Bibi, Imran Abdullah, Hafsa Ashfaq, Salim Jamil, Ahmed Al-Emam
Published: 202610.1016/j.tice.2025.103213
Abstract
Acyclovir (ACR) is a potent anti-viral drug that exhibited pronounced effects on different organs including renal toxicity. Medicarpin (MED) is a novel polyphenolic compound that exhibits strong pharmacological properties. The current research projec…
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