Tissue & cellAnimalsToll-Like Receptor 4MaleRatsSprague-Dawley
Homopterocarpin alleviates methoxychlor-induced hepatotoxicity via modulating thioredoxin/peroxiredoxin and TLR4/MyD88 pathway: A comprehensive biochemical, histopathological, and computational analysis.
Mansour Abdulaziz Alsaleem, Salim Jamil, Abdulaziz Saleh Alkhoshaiban, Muhammad Bilal Azmat, Ahmed Al-Emam, Hesham M Hassan
Published: 202610.1016/j.tice.2025.103174
Abstract
Methoxychlor (MET) is a synthetic organo-chlorine insecticide that is known to exert deleterious effects on hepatic tissues. Homopterocarpin (HTP) isa bioactive compound that possess highly valuable pharmacological effects. Thirty-six male albino Spr…
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