Tissue & cellAnimalsFlavanonesFluorouracilApoptosisOxidative Stress
Naringenin mitigates 5-fluorouracil-induced nephrotoxicity by decreasing oxidative stress, inflammation and apoptosis.
Fatih Mehmet Gür, Sedat Bilgiç, İbrahim Aktaş
Published: 202610.1016/j.tice.2025.103170
Abstract
The toxic effects of 5-fluorouracil (5-FU), a drug widely used in the treatment of neoplasms and primarily excreted through the urine, prompted us to investigate the protective potential of naringenin (NAR) against nephrotoxicity induced by 5-FU. In…
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