Trends in biotechnology
A synthetic biology roadmap for sustainable production of the plant-originated anti-cancer drug paclitaxel.
Chun-Lin Tan, Xin Yu, Hui-Cheng Feng, Jonathan Gershenzon, Yan Liu, Sheng-Hong Li
Published: 202610.1016/j.tibtech.2025.11.013
Abstract
Paclitaxel, a clinically potent anticancer drug derived from Taxus species, faces persistent challenges in sustainable supply. Synthetic biology presents substantial opportunities for its de novo production, particularly with recent breakthroughs in…
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