TheriogenologyAnimalsOocytesCattleEmbryonic DevelopmentIn Vitro Oocyte Maturation Techniques
α-Ketoglutarate enhances bovine oocyte maturation and embryo development: insights from metabolomic and transcriptomic profiling.
Yassin Kassim, Guangjun Xu, Hao Sheng, Hao Jin, Tariq Iqbal, Mostafa Elashry, Omaima Mohamed Kandil, Esraa Aly Ismail, Kun Zhang
Published: 202610.1016/j.theriogenology.2025.117723
Abstract
Oocyte quality, governed by metabolic and epigenetic regulation, is essential for fertilization and embryogenesis. This study aimed to elucidate the dose-dependent and multifaceted roles of α-ketoglutarate (α-KG) in modulating the molecular and metab…
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