TheriogenologyAnimalsCyclic GMPSheepCryopreservationLipid Metabolism
Cyclic guanosine monophosphate (cGMP) improves freezing tolerance of sheep embryos by reducing lipid content.
Nan Zhang, Cun Zhao, Yupeng Sun, Yukun Song, Yaxin Guo, Wui Sun, Zhiying Wang, Jiaxin Zhang
Published: 202610.1016/j.theriogenology.2025.117685
Abstract
Embryos produced in vitro exhibit heightened cryosensitivity due to excessive lipid accumulation. Previous studies demonstrated that cyclic guanosine monophosphate (cGMP) modulates intracellular lipid metabolism through cGMP-dependent protein kinase…
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