Trends in endocrinology and metabolism: TEM
SLC25A45: a gatekeeper for methylated amino acid metabolism.
Yue Zhang, Yan Tian, Xianghui Fu
Published: 202610.1016/j.tem.2025.12.005
Abstract
The metabolite substrates of numerous transporters remain largely elusive. Two recent studies by Khan et al. and Dias et al. identify SLC25A45 as a mitochondrial transporter of methylated amino acids that supports de novo carnitine synthesis, providi…
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