TalantaNeuraminidaseUltrafiltrationBiological ProductsEnzyme InhibitorsLigands
Competitive ultrafiltration: A ligand-displacement strategy for rapid discovery of high-quality neuraminidase inhibitors from natural product mixtures.
Menghan Chen, Cheng Tian, Tongtong Jian, Yongli Wei, Yizhou Xin
Published: 202610.1016/j.talanta.2025.128948
Abstract
The rapid discovery of high-quality natural products (NPs) that combine potent biological activity with structural diversity remains a major challenge. Traditional bioactivity-guided isolation is time-consuming and labor-intensive, and although the d…
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