Toxicology and applied pharmacologyAnimalsMaleLiverKidneyRats
Evaluation of 2-isopropyl-N-2,3-trimethylbutyramide by a comprehensive toxicity study using gpt delta rats.
Tatsuya Mitsumoto, Yuji Ishii, Norifumi Takimoto, Shinji Takasu, Moeka Namiki, Takeshi Toyoda, Kumiko Ogawa
Published: 202610.1016/j.taap.2025.117686
Abstract
2-Isopropyl-N-2,3-trimethylbutyramide (ITB) is a food-flavoring agent classified as an aliphatic amide. In 2016, the Joint FAO/WHO Expert Committee on Food Additives evaluated ITB and concluded that additional data on toxicity and in vivo genotoxicit…
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