Toxicology and applied pharmacology
Generation and distribution of cyanide in rats and humans following sodium cyanoborohydride exposure.
Zhenshuo Guo, Yiling Tang, Ruilin Zhang, Yu Ma, Ruxin Luo, Ping Xiang, Hui Yan, Wenjia Duan
Published: 202510.1016/j.taap.2025.117592
Abstract
Sodium cyanoborohydride (NaBH3CN) is a commonly used reducing agent. However, its metabolism and mechanism of toxicity are still unclear. In this study, we first demonstrated that NaBH3CN underwent rapid hydrolysis in aqueous solution and produced hy…
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