Toxicology and applied pharmacology
cGAS-STING pathway mediates TiO2 nanoparticle-induced TM4 cell apoptosis via MCUb downregulation and calcium overload.
Pengfei Li, Chenhao Sun, Qianqian Wang, Yunhua Hu, Guanling Song
Published: 202510.1016/j.taap.2025.117591
Abstract
Titanium dioxide nanoparticles (TiO2 NPs) pose potential reproductive toxicity risks, notably compromising the blood-testis barrier (BTB), for which Sertoli cells are pivotal in maintaining integrity. However, certain research gaps remain regarding t…
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