Structure (London, England : 1993)InsulinInsulin-Secreting CellsSecretory VesiclesAnimalsHumans
Soft X-ray tomography illuminates drug-induced changes in insulin granules.
Natalia Fuchs, Venera Weinhardt
Published: 202510.1016/j.str.2025.10.007
Abstract
In this issue of Structure, Deshmukh et al.1 reveal that β cells actively remodel insulin secretory granules in response to specific physiological cues, altering granule density, proinsulin processing, and spatial distribution. This stimulus-specific…
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