SteroidsHumansChildMaleBiomarkersAnti-Inflammatory Agents
Exposure-response of serum biomarkers to vamorolone, a dissociative corticosteroidal anti-inflammatory drug, in 4- to <7-year children.
Swati Mummidivarpu, Utkarsh J Dang, Michael Ziemba, Yetrib Hathout, Paula R Clemens, Jesse Damsker, Laura Hagerty, William J Jusko, Edward C Smith, Jean K Mah, Michela Guglieri, Yoram Nevo, Nancy Kuntz, Craig M McDonald, Monique M Ryan
Published: 202610.1016/j.steroids.2025.109721
Abstract
OBJECTIVES: Corticosteroid agonists of the glucocorticoid receptor are a mainstay of therapeutics for pro-inflammatory conditions. Vamorolone is a novel partial agonist that is differentiated from the other members of the corticosteroid class by non-…
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